Pattern clusters we keep seeing, with what we see differently per cluster and the markers we read by default. List grows with every new pattern.
Fatigue
Iron deficiency and T3-conversion block often coexist. TSH alone misses it. Cortisol rhythm reveals if it's HPA-axis driven.
Markers:Iron status, thyroid profile, B12, vit D, magnesium, cortisol rhythm
Brain fog
Elevated homocysteine signals methylation block (B12, folate, B6). More often the cause than vit D alone.
Markers:B12, homocysteine, thyroid, vit D, magnesium, HbA1c
Hormonal symptoms
SHBG explains why free testosterone deviates while total reads normal. Cortisol + DHEA-S together reveal adrenal balance.
Markers:Sex hormones, thyroid, cortisol, prolactin, SHBG, DHEA-S
Joint pain
CRP and ESR together distinguish acute from chronic inflammation. Vit D below optimum raises joint pain prevalence regardless of osteoarthritis.
Markers:Vit D, CRP, ESR, uric acid, anti-CCP, RA factor, ANA
Skin issues
Zinc deficiency is often underestimated as an active driver of acne and eczema. Ferritin below optimum stresses skin before anemia shows.
Markers:Zinc, vit D, IgE, ferritin, thyroid, B-complex
Gut & digestion
Calprotectin differentiates IBD from IBS. Ferritin and B12 together reveal absorption status, not one marker alone.
Markers:tTG-IgA, calprotectin, ferritin, B12, vit D, zinc
Sleep
High evening cortisol with low morning cortisol points to HPA inversion. Ferritin below 50 disrupts restless-leg physiology.
Markers:Cortisol rhythm, ferritin, thyroid, vit D, magnesium, B6
Weight & metabolic
Insulin and HOMA-IR show insulin resistance years before diabetes diagnosis. Thyroid-conversion block explains metabolic sluggishness at normal TSH.
Markers:Fasting glucose, HbA1c, insulin, HOMA-IR, thyroid, cholesterol panel
›Marker groups we also read
Iron
Ferritin, transferrin saturation, MCV, MCH, B12, folate
Thyroid
TSH, free T4, free T3, anti-TPO, reverse T3
Cardiovascular
Cholesterol panel, LDL, HDL, ApoB, Lp(a), homocysteine
Liver & kidney
ALAT, ASAT, gGT, creatinine, eGFR, urea
Inflammation
CRP, ESR, fibrinogen, ferritin
Micronutrients
Vit D, B-complex, magnesium, zinc, iodine
Metabolic
Fasting glucose, HbA1c, insulin, HOMA-IR
Autoimmune & allergy
ANA, RA factor, anti-CCP, total IgE